Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 6/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7010122 | 0.92 | ADRB2 (0.43) | ADRB2HPGDTOP2ATOP2BMEN1 | |
| SCHEMBL7008331 | 0.92 | TOP2A (0.47) | HPGDTOP2ATOP2BMEN1KMT2A | |
| SCHEMBL7007102 | 0.91 | ADRB2 (0.42) | ADRB2HPGDTOP2ATOP2BMEN1 | |
| SCHEMBL7008688 | 0.90 | ADRB2 (0.45) | ADRB2HPGDTOP2ATOP2BMEN1 | |
| SCHEMBL7010320 | 0.90 | TOP2A (0.49) | ADRB2HPGDTOP2ATOP2BMEN1 | |
| SCHEMBL7504090 | 0.89 | HPGD (0.39) | ADRB2HPGDMEN1MAPTTHRB | |
| SCHEMBL7008129 | 0.89 | ADRB2 (0.44) | ADRB2HPGDTOP2ATOP2BMEN1 | |
| SCHEMBL7012238 | 0.89 | ADRB2 (0.41) | ADRB2HPGDTOP2ATOP2BMEN1 | |
| SCHEMBL7500976 | 0.84 | ADRB2 (0.38) | ADRB2HPGDTOP2ATOP2BMEN1 | |
| SCHEMBL7007624 | 0.84 | TOP2A (0.49) | HPGDTOP2ATOP2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775702-B1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-5935952-A | ANTIBACTERIAL AGENT | TOYAMA CHEMICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0775702-A1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 1997-05-28 | — | — | EP | disclosed |