Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 19/20 | 0.53 |
| ▸ | CTSL | P07711 | 16/20 | 0.53 |
| ▸ | CTSS | P25774 | 12/20 | 0.53 |
| ▸ | CTSB | P07858 | 6/20 | 0.53 |
| ▸ | CTSV | O60911 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7014111 | 0.87 | CTSK (0.64) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4689513 | 0.80 | CTSK (0.67) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL7571991 | 0.76 | CTSK (0.64) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL7013531 | 0.75 | CTSK (0.40) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL14131372 | 0.74 | CTSK (0.82) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL14040700 | 0.74 | CTSK (0.82) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL7435727 | 0.74 | CTSK (0.77) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4690508 | 0.73 | CTSK (0.74) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5141688 | 0.73 | CTSK (0.75) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4765813 | 0.72 | CTSK (0.73) | CTSKCTSLCTSSCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1278502-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2003-05-21 | — | — | EP | claimed |
| EP-1278502-A2 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2003-01-29 | — | — | EP | claimed |
| WO-2001089451-A2 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-11-29 | — | — | WO | claimed |
| EP-1280798-A1 | BICYCLIC HETEROCYLCES, MEDICAMENTS CONTAINING SAID COMPOUNDS, THE USE THEREOF AND METHOD FOR PRODUCING THEM | Boehringer Ingelheim Pharma KG (DE) | 2003-02-05 | — | — | EP | disclosed |
| WO-2001077104-A1 | BICYCLIC HETEROCYLCES, MEDICAMENTS CONTAINING SAID COMPOUNDS, THE USE THEREOF AND METHOD FOR PRODUCING THEM | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2001-10-18 | — | — | WO | disclosed |