Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 17/20 | 0.40 |
| ▸ | CTSS | P25774 | 14/20 | 0.40 |
| ▸ | CTSL | P07711 | 13/20 | 0.40 |
| ▸ | CTSB | P07858 | 5/20 | 0.40 |
| ▸ | CTSV | O60911 | 1/20 | 0.39 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7015060 | 0.83 | CTSK (0.57) | CTSKCTSSCTSLCTSBCTSV | |
| SCHEMBL7148228 | 0.80 | CTSK (0.51) | CTSKCTSSCTSLCTSBCTSV | |
| SCHEMBL6765719 | 0.76 | CTSK (0.52) | CTSKCTSSCTSLCTSBCTSV | |
| SCHEMBL7010402 | 0.75 | CTSK (0.53) | CTSKCTSSCTSLCTSBCTSV | |
| SCHEMBL4763021 | 0.73 | CTSK (0.57) | CTSKCTSSCTSLCTSBCTSV | |
| SCHEMBL13784228 | 0.72 | CTSS (0.46) | CTSKCTSSCTSLCTSBCTSV | |
| SCHEMBL6842086 | 0.72 | CTSK (0.74) | CTSKCTSSCTSLCTSBCTSV | |
| SCHEMBL4768304 | 0.71 | CTSK (0.55) | CTSKCTSSCTSLCTSBCTSV | |
| SCHEMBL6740265 | 0.71 | CTSK (0.59) | CTSKCTSSCTSLCTSBCTSV | |
| SCHEMBL6740268 | 0.71 | CTSK (0.59) | CTSKCTSSCTSLCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1278502-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2003-05-21 | — | — | EP | disclosed |
| EP-1278502-A2 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2003-01-29 | — | — | EP | disclosed |
| WO-2001089451-A2 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-11-29 | — | — | WO | disclosed |