Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.30 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10516761 | 0.87 | CA12 (0.34) | ALDH1A1L3MBTL1 | |
| SCHEMBL7007713 | 0.86 | MEN1 (0.37) | LMNAALDH1A1GAASMN1; SMN2NPSR1 | |
| SCHEMBL7004956 | 0.83 | ALDH1A1 (0.35) | LMNAALDH1A1TSHRL3MBTL1 | |
| SCHEMBL10510642 | 0.78 | CES2 (0.46) | LMNAALDH1A1NPSR1TSHRL3MBTL1 | |
| SCHEMBL6184304 | 0.76 | HSD17B2 (0.40) | LMNAALDH1A1TSHRL3MBTL1 | |
| SCHEMBL8735860 | 0.75 | MEN1 (0.38) | LMNAALDH1A1GAASMN1; SMN2NPSR1 | |
| SCHEMBL7005407 | 0.74 | ALDH1A1 (0.41) | ALDH1A1GAASMN1; SMN2NPSR1TSHR | |
| SCHEMBL3190052 | 0.74 | CES2 (0.39) | ALDH1A1L3MBTL1 | |
| SCHEMBL10830983 | 0.73 | CES2 (0.47) | ALDH1A1GAASMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL9046842 | 0.72 | CES2 (0.37) | LMNASMN1; SMN2TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775702-B1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-5935952-A | ANTIBACTERIAL AGENT | TOYAMA CHEMICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0775702-A1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 1997-05-28 | — | — | EP | disclosed |