SCHEMBL7010519

SCHEMBL7010519

Nc1cc(O)n(-c2ccccc2)n1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2C19 P33261 1/20 0.48
SMN1; SMN2 Q16637 6/20 0.44
POLB P06746 1/20 0.44
KMT2A Q03164 3/20 0.44
RAB9A P51151 5/20 0.43
ALDH1A1 P00352 3/20 0.43
MEN1 O00255 2/20 0.43
TSHR P16473 2/20 0.43
GFER P55789 1/20 0.43
TDP2 O95551 1/20 0.43
CHEK1 O14757 1/20 0.41
AURKA O14965 1/20 0.41
CSNK1A1 P48729 1/20 0.41
CDK8 P49336 1/20 0.41
NEK2 P51955 1/20 0.41
LIMK1 P53667 1/20 0.41
CDK5 Q00535 1/20 0.41
DYRK1A Q13627 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7837159 0.81 CYP1A2 (0.66) MAPK1CYP1A2CYP2C19SMN1; SMN2POLB
SCHEMBL10715419 0.78 MAPK1 (0.42) MAPK1CYP1A2CYP2C19SMN1; SMN2KMT2A
SCHEMBL11274702 0.78 CYP1A2 (0.47) MAPK1CYP1A2CYP2C19SMN1; SMN2POLB
SCHEMBL3487668 0.78 MAPK1 (0.56) MAPK1CYP1A2CYP2C19SMN1; SMN2POLB
SCHEMBL14814324 0.78 CYP1A2 (0.47) MAPK1CYP1A2CYP2C19SMN1; SMN2POLB
SCHEMBL3180813 0.77 CYP1A2 (0.43) MAPK1CYP1A2CYP2C19SMN1; SMN2POLB
SCHEMBL11472621 0.76 RAB9A (0.62) MAPK1CYP1A2CYP2C19SMN1; SMN2KMT2A
SCHEMBL10940264 0.75 LMNA (0.59) MAPK1CYP1A2CYP2C19SMN1; SMN2KMT2A
SCHEMBL200831 0.75 MAPK1 (0.63) MAPK1CYP1A2CYP2C19SMN1; SMN2KMT2A
SCHEMBL7010515 0.75 MAPK1 (0.40) MAPK1CYP1A2CYP2C19SMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0970084-B1 PYRROLO 2,3D]PYRIMIDINES AND THEIR USE AS TYROSINE KINASE INHIBITORS BASF AG (DE) 2003-06-04 EP claimed
EP-1739134-B1 Azo Compounds FUJIFILM CORP (JP) 2011-12-07 EP disclosed
US-7632615-B2 Colorant-containing curable composition, color filter using the composition, and method for manufacturing the same FUJIFILM CORPORATION (JP) 2009-12-15 US disclosed
US-7632615-B2 Colorant-containing curable composition, color filter using the composition, and method for manufacturing the same FUJIFILM CORPORATION (JP) 2009-12-15 US disclosed
US-7399843-B2 Colorant-containing curable composition, color filter using the composition, and method for manufacturing the same FUJIFILM CORPORATION (JP) 2008-07-15 US disclosed
US-7399843-B2 Colorant-containing curable composition, color filter using the composition, and method for manufacturing the same FUJIFILM CORPORATION (JP) 2008-07-15 US disclosed
US-20080021223-A1 Colorant-Containing Curable Composition, Color Filter Using The Composition, and Method For Manufacturing The Same FUJIFILM CORPORATION (JP) 2008-01-24 US disclosed
US-20080021223-A1 Colorant-Containing Curable Composition, Color Filter Using The Composition, and Method For Manufacturing The Same FUJIFILM CORPORATION (JP) 2008-01-24 US disclosed
US-20080014536-A1 Colorant-Containing Curable Composition, Color Filter Using The Composition, And Method For Manufacturing The Same FUJIFILM CORPORATION (JP) 2008-01-17 US disclosed
US-20080014536-A1 Colorant-Containing Curable Composition, Color Filter Using The Composition, And Method For Manufacturing The Same FUJIFILM CORPORATION (JP) 2008-01-17 US disclosed
US-7276548-B2 Colorant-containing curable composition, color filter using the composition, and method for manufacturing the same FUJIFILM CORPORATION (JP) 2007-10-02 US disclosed
US-7276548-B2 Colorant-containing curable composition, color filter using the composition, and method for manufacturing the same FUJIFILM CORPORATION (JP) 2007-10-02 US disclosed
EP-1739134-A1 AZO COMPOUND Fuji Photo Film Co., Ltd. (JP) 2007-01-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080021223-A1 Colorant-Containing Curable Composition, Color Filter Using The Composition, and Method For Manufacturing The Same CRKL, RB1, CARM1 MAPK1 1904/4885CYP1A2 1246/4885CYP2C19 1627/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.