Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 16/20 | 0.44 |
| ▸ | HTR1D | P28221 | 2/20 | 0.41 |
| ▸ | HTR1B | P28222 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7012792 | 1.00 | HTR6 (0.44) | HTR6HTR1DHTR1B | |
| SCHEMBL7010546 | 1.00 | HTR6 (0.44) | HTR6HTR1DHTR1B | |
| SCHEMBL8979687 | 0.84 | HTR6 (0.43) | HTR6HTR1DHTR1B | |
| SCHEMBL7006185 | 0.78 | HTR6 (0.46) | HTR6HTR1DHTR1B | |
| SCHEMBL8979664 | 0.78 | HTR6 (0.45) | HTR6HTR1DHTR1B | |
| SCHEMBL19150272 | 0.78 | HTR6 (0.45) | HTR6HTR1DHTR1B | |
| SCHEMBL7013305 | 0.77 | HTR6 (0.39) | HTR6HTR1DHTR1B | |
| SCHEMBL7010382 | 0.77 | HTR6 (0.39) | HTR6HTR1DHTR1B | |
| SCHEMBL7481650 | 0.76 | CNR2 (0.47) | HTR6HTR1DHTR1B | |
| SCHEMBL1697459 | 0.76 | HTR6 (0.46) | HTR6HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098896-B1 | 5-BICYCLOINDOLE COMPOUNDS | NPS ALLELIX CORP (CA) | 2003-06-25 | — | — | EP | disclosed |
| US-6329390-B1 | BIHETEROCYCLIC INDOLES AS ANALGESICS AND NERVOUS SYSTEM DISORDERS | NPS ALLELIX CORP. (CA) | 2001-12-11 | — | — | US | disclosed |
| EP-1098896-A1 | 5-BICYCLOINDOLE COMPOUNDS | NPS Allelix Corp. (CA) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000004019-A1 | 5-BICYCLOINDOLE COMPOUNDS | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 2000-01-27 | — | — | WO | disclosed |