Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7008974 | 0.82 | F10 (0.47) | F10ALDH1A1KDM4EHPGD | |
| SCHEMBL7012908 | 0.79 | GAA (0.55) | F10ALDH1A1KDM4E | |
| SCHEMBL7011601 | 0.79 | F10 (0.56) | F10ALDH1A1KMT2AKDM4EHPGD | |
| SCHEMBL6791925 | 0.77 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGD | |
| SCHEMBL7016117 | 0.77 | CA1 (0.51) | F10ALDH1A1HPGD | |
| SCHEMBL7014747 | 0.76 | F10 (0.46) | F10ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL7014861 | 0.76 | GAA (0.54) | F10ALDH1A1KDM4EHPGD | |
| Trifluoroacetic Acid SCHEMBL7014625 | 0.75 | F10 (0.46) | F10ALDH1A1KDM4EHPGDPTGDR2 | |
| SCHEMBL7017324 | 0.75 | F10 (0.53) | F10ALDH1A1KMT2AKDM4EHPGD | |
| SCHEMBL7015561 | 0.75 | CA2 (0.51) | F10ALDH1A1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030187023-A1 | Sulfone derivatives, process for their production and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-10-02 | — | — | US | disclosed |
| EP-1302462-A1 | SULFONE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2003-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187023-A1 | Sulfone derivatives, process for their production and use thereof | SULT1E1, RRS1, SHH | F10 717/4885ALDH1A1 4317/4885MEN1 1401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.