SCHEMBL7010849

SCHEMBL7010849

CC(=O)C(NC(=N)N)(NC(=N)N)C(=O)O

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.30
ALOX15 P16050 1/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL508182 0.85 CYP2C19 (0.33)
SCHEMBL17030024 0.71 KDM4C (0.42)
SCHEMBL3498204 0.70 NAALAD2 (0.33)
SCHEMBL28072399 0.69 ALDH1A1 (0.30)
SCHEMBL5275977 0.65 MEN1 (0.35)
Acetic Acid SCHEMBL19458352 0.64 FFAR3 (0.44) LMNAALOX15BLMPMP22
Biguanide SCHEMBL28444535 0.64 FFAR3 (0.44) LMNAALOX15BLMPMP22
Pimagedine SCHEMBL1065359 0.64
Acetic Acid SCHEMBL30784964 0.64 FFAR3 (0.44) LMNAALOX15BLMPMP22
Biguanide SCHEMBL28833765 0.64 FFAR3 (0.44) LMNAALOX15BLMPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0860438-B1 Fluorine-containing diphenyl acrylamide antimicrobial agents SHENYANG RES INST CHEMICAL IND (CN) 2003-01-08 EP disclosed
US-6020332-A Fluorine-containing diphenyl acrylamide antimicrobial agents SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY (CN) 2000-02-01 US disclosed
EP-0860438-A1 Fluorine-containing diphenyl acrylamide antimicrobial agents Shenyang Research Institute of Chemical Industry (CN) 1998-08-26 EP disclosed