Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7016499 | 0.84 | SMN1; SMN2 (0.44) | MEN1KMT2ACYP2A6SMN1; SMN2GAA | |
| SCHEMBL9364458 | 0.81 | PTGS1 (0.42) | PTGS1AKR1C3AKR1C2MEN1KMT2A | |
| SCHEMBL11469720 | 0.80 | ALDH1A1 (0.51) | PTGS1AKR1C3AKR1C2MEN1KMT2A | |
| SCHEMBL11463930 | 0.75 | ALDH1A1 (0.50) | PTGS1AKR1C3AKR1C2GSK3AMAPK10 | |
| SCHEMBL5239907 | 0.74 | PTGS1 (0.45) | PTGS1AKR1C3AKR1C2MEN1KMT2A | |
| SCHEMBL11469526 | 0.72 | PTGS1 (0.59) | PTGS1AKR1C3AKR1C2MEN1KMT2A | |
| SCHEMBL11661526 | 0.70 | CYP2A6 (0.50) | KMT2ACYP2A6CCR2 | |
| SCHEMBL14018676 | 0.70 | CYP2A6 (0.61) | AKR1C3AKR1C2KMT2ACYP2A6SMN1; SMN2 | |
| SCHEMBL7010851 | 0.70 | PTGS1 (0.41) | PTGS1AKR1C3AKR1C2MEN1KMT2A | |
| SCHEMBL7009082 | 0.70 | CYP1A2 (0.39) | L3MBTL1SMN1; SMN2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030187023-A1 | Sulfone derivatives, process for their production and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-10-02 | — | — | US | disclosed |
| EP-1302462-A1 | SULFONE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2003-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187023-A1 | Sulfone derivatives, process for their production and use thereof | SULT1E1, RRS1, SHH | PTGS1 1597/4885AKR1C3 2276/4885AKR1C2 2322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.