Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.36 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7010853 | 0.81 | PTGS1 (0.41) | PTGS1AKR1C3AKR1C2GAAALDH1A1 | |
| SCHEMBL7632091 | 0.74 | LMNA (0.49) | ALDH1A1IDO1TDP1PKMLMNA | |
| SCHEMBL6349150 | 0.71 | TRPA1 (0.64) | AKR1C3AKR1C2ALOX5RIOK2POLB | |
| SCHEMBL11275952 | 0.71 | GAA (0.68) | PTGS1AKR1C3AKR1C2GAAALDH1A1 | |
| SCHEMBL9364456 | 0.69 | PTGS1 (0.42) | PTGS1AKR1C3AKR1C2GAAALDH1A1 | |
| SCHEMBL21620954 | 0.68 | ALDH1A1 (0.61) | PTGS1AKR1C3AKR1C2GAAALDH1A1 | |
| SCHEMBL14756847 | 0.68 | MAPT (0.70) | PTGS1ALDH1A1GFERTSHRNFKB1 | |
| SCHEMBL6338759 | 0.67 | ASIC3 (0.47) | PTGS1GAAALDH1A1GFERTDP1 | |
| SCHEMBL7324968 | 0.67 | ALDH1A1 (0.45) | GAAALDH1A1MEN1KMT2AAKR1B1 | |
| Hydrochloric Acid SCHEMBL11276012 | 0.67 | RAD52 (0.42) | ALDH1A1GFERIDO1IGF1RPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0419676-B1 | THIONAPHTHALENE DERIVATIVES, METHOD OF PRODUCING THE SAME, AND ANTIALLERGIC AGENT CONTAINING THE SAME | TEIJIN LTD (JP) | 1994-12-07 | — | — | EP | disclosed |
| EP-0419676-A1 | THIONAPHTHALENE DERIVATIVES, METHOD OF PRODUCING THE SAME, AND ANTIALLERGIC AGENT CONTAINING THE SAME | TEIJIN LIMITED (JP) | 1991-04-03 | — | — | EP | disclosed |