Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.39 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.35 |
| ▸ | ABAT | P80404 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 2/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10532733 | 0.85 | CA1 (0.45) | TRIM24TRIM33ALDH5A1ABATTYR | |
| SCHEMBL9827652 | 0.82 | ERN1 (0.43) | TRIM24TRIM33ALDH5A1ABATTYR | |
| 4-Hydroxybenzaldehyde SCHEMBL7455404 | 0.76 | TRIM24 (0.56) | TRIM24TRIM33ALDH5A1ABATCA1 | |
| 4-Hydroxybenzaldehyde SCHEMBL27623564 | 0.74 | TRIM24 (0.55) | TRIM24TRIM33ALDH5A1ABATCA1 | |
| 4-Hydroxybenzaldehyde SCHEMBL4952623 | 0.74 | TRIM24 (0.72) | TRIM24TRIM33ALDH5A1ABATCA1 | |
| Hydroquinone SCHEMBL28407198 | 0.74 | ERN1 (0.55) | TRIM24TRIM33ALDH5A1ABATTYR | |
| Salicyladehyde SCHEMBL7038124 | 0.73 | TRIM24 (0.53) | TRIM24TRIM33CYP1A2CYP2C19TYR | |
| Metacresol SCHEMBL28223396 | 0.73 | ACHE (0.57) | TRIM24TRIM33CYP1A2CYP2C19TYR | |
| Salicyladehyde SCHEMBL7034198 | 0.71 | TRIM24 (0.62) | TRIM24TRIM33CYP1A2CYP2C19TYR | |
| Resorcinol SCHEMBL11728630 | 0.71 | ERN1 (0.52) | TRIM24TRIM33CYP1A2CYP2C19TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1267874-A2 | THERAPEUTIC USES OF PPAR MEDIATORS | Aventis Pharma Deutschland GmbH (DE) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001066098-A2 | THERAPEUTIC USES OF PPAR MEDIATORS | AVENTIS PHARMA DEUTSCHLAND GMBH | 2001-09-13 | — | — | WO | disclosed |