4-Hydroxybenzaldehyde

4-Hydroxybenzaldehyde

SCHEMBL7455404

O=Cc1ccc(O)cc1.O=Cc1cccc(O)c1.O=Cc1ccccc1O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 1/20 0.56
TRIM33 Q9UPN9 1/20 0.56
ALDH5A1 P51649 1/20 0.50
ABAT P80404 1/20 0.50
ERN1 O75460 1/20 0.44
LCK P06239 2/20 0.44
CCNB2 O95067 1/20 0.44
CDK1 P06493 1/20 0.44
CDK4 P11802 1/20 0.44
CCNB1 P14635 1/20 0.44
CCND1 P24385 1/20 0.44
CCNB3 Q8WWL7 1/20 0.44
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
HSP90AA1 P07900 1/20 0.43
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
KDM4E B2RXH2 1/20 0.42
PTGS2 P35354 1/20 0.42
RAB9A P51151 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Hydroxybenzaldehyde SCHEMBL27623564 0.98 TRIM24 (0.55) TRIM24TRIM33ALDH5A1ABATERN1
3-Hydroxybenzaldehyde SCHEMBL10405026 0.94 TRIM24 (0.64) TRIM24TRIM33ERN1LCKCCNB2
4-Hydroxybenzaldehyde SCHEMBL4952623 0.88 TRIM24 (0.72) TRIM24TRIM33ALDH5A1ABATERN1
4-Hydroxybenzaldehyde SCHEMBL15936324 0.87 ALDH5A1 (0.67) ALDH5A1ABATLCKCCNB2CDK1
3-Hydroxybenzaldehyde SCHEMBL8007436 0.83 TYR (0.51) TRIM24TRIM33ALDH5A1ABATLCK
Salicyladehyde SCHEMBL27460666 0.83 TRIM24 (0.75) TRIM24TRIM33ERN1CCNB2CDK1
Salicyladehyde SCHEMBL7038124 0.82 TRIM24 (0.53) TRIM24TRIM33ERN1CCNB2CDK1
Salicyladehyde SCHEMBL4985603 0.81 TRIM24 (0.78) TRIM24TRIM33ALDH5A1ABATERN1
3-Hydroxybenzaldehyde SCHEMBL2230842 0.81 CCNB2 (0.57) ALDH5A1ABATLCKCCNB2CDK1
3-Hydroxybenzaldehyde SCHEMBL29155415 0.81 ALDH1A1 (0.61) ALDH5A1ABATLCKCCNB2CDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1030665-A4 THERAPEUTIC USES OF QUINOLINE DERIVATIVES AVENTIS PHARM PROD INC (US) 2002-11-27 EP disclosed
EP-1030665-A1 THERAPEUTIC USES OF QUINOLINE DERIVATIVES Aventis Pharmaceuticals Products Inc. (US) 2000-08-30 EP disclosed
WO-1999020275-A1 THERAPEUTIC USES OF QUINOLINE DERIVATIVES AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) 1999-04-29 WO disclosed