SCHEMBL70120

SCHEMBL70120

COC(=O)c1ccc(C(=O)OC)n1-c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.52
ALDH1A1 P00352 6/20 0.50
HPGD P15428 4/20 0.50
ALOX15 P16050 3/20 0.50
HSD17B10 Q99714 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
MAPT P10636 6/20 0.48
KDM4E B2RXH2 5/20 0.48
PKM P14618 2/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2D6 P10635 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
GAA P10253 3/20 0.47
NPSR1 Q6W5P4 1/20 0.46
NR4A2 P43354 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
LMNA P02545 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15466939 0.78 ALDH1A1 (0.69) TSHRALDH1A1HPGDALOX15HSD17B10
SCHEMBL15005391 0.77 ALDH1A1 (0.70) TSHRALDH1A1HPGDALOX15HSD17B10
SCHEMBL69748 0.76 ALDH1A1 (0.57) TSHRALDH1A1HPGDALOX15MAPT
SCHEMBL19284321 0.76 NR4A2 (0.50) TSHRALDH1A1ALOX15HSD17B10SMN1; SMN2
SCHEMBL5088290 0.73 MAPT (0.55) TSHRALDH1A1HPGDALOX15HSD17B10
SCHEMBL18394893 0.73 TP53 (0.50) TSHRALDH1A1HPGDHSD17B10SMN1; SMN2
SCHEMBL11791554 0.73 HPGD (0.59) ALDH1A1HPGDALOX15HSD17B10SMN1; SMN2
SCHEMBL16237303 0.72 TSHR (0.46) TSHRALDH1A1SMN1; SMN2MAPTKDM4E
SCHEMBL8299631 0.72 MTNR1A (0.59) TSHRALDH1A1HPGDALOX15HSD17B10
SCHEMBL15004952 0.72 ALDH1A1 (0.47) TSHRALDH1A1HPGDALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 TSHR 3263/4885ALDH1A1 1882/4885HPGD 3275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.