Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23354998 | 0.71 | LMNA (0.30) | KDM4ELMNASMN1; SMN2GAA | |
| SCHEMBL29851913 | 0.71 | LMNA (0.30) | KDM4ELMNASMN1; SMN2GAA | |
| SCHEMBL5394 | 0.71 | KDM4E (0.35) | KDM4ELMNA | |
| SCHEMBL30503678 | 0.71 | KDM4E (0.35) | KDM4ELMNA | |
| Water SCHEMBL5968353 | 0.69 | KDM4E (0.34) | KDM4ELMNA | |
| SCHEMBL1186165 | 0.69 | SMN1; SMN2 (0.36) | KDM4ELMNASMN1; SMN2 | |
| SCHEMBL1186717 | 0.69 | CA1 (0.34) | KDM4EGAAPOLB | |
| SCHEMBL31057488 | 0.67 | PRKCI (0.42) | — | |
| SCHEMBL17546638 | 0.67 | CCR1 (0.40) | — | |
| SCHEMBL18614442 | 0.67 | AXL (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0662078-B1 | REAGENTS FOR PEPTIDE COUPLINGS | RES CORP TECHNOLOGIES INC (US) | 2003-05-02 | — | — | EP | disclosed |
| US-RE38073-E1 | Biosynthesis; using dehydration agent | RESEARCH CORPORATIONS TECHNOLOGIES, INC. | 2003-04-08 | — | — | US | disclosed |
| US-RE37686-E1 | Azahydroxybenzotriazoles and derivatives thereof for peptide coupling reactions | RESEARCH CORPORATION TECHNOLOGIES, INC. | 2002-04-30 | — | — | US | disclosed |
| US-5698675-A | AMIDATION; ESTERIFICATION | RESEARCH CORPORATION TECH., INC. (US) | 1997-12-16 | — | — | US | disclosed |
| US-5644029-A | TRIAZOLO-PYRIDINE HETEROCYCLIC COMPOUNDS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5580981-A | YELLOW INDICATORS FADING TO COLORLESS UPON COMPLETION OF THE ACYLATION STEP IN AMIDE FORMATION; REACTION ACCELERATORS; LOWERS RACEMIZATION | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1996-12-03 | — | — | US | disclosed |
| EP-0662078-A1 | NEW REAGENTS FOR PEPTIDE COUPLINGS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-07-12 | — | — | EP | disclosed |
| WO-1994007910-A1 | NEW REAGENTS FOR PEPTIDE COUPLINGS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1994-04-14 | — | — | WO | disclosed |