Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.30 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857499 | 0.75 | GRIN2B (0.35) | TSHR | |
| SCHEMBL1453582 | 0.74 | TSHR (0.46) | TSHRALDH1A1HPGD | |
| SCHEMBL2389905 | 0.72 | DRD2 (0.43) | TSHR | |
| SCHEMBL1983658 | 0.72 | TSHR (0.32) | TSHR | |
| SCHEMBL3914612 | 0.71 | SKP2 (0.56) | TSHRARALDH1A1HPGD | |
| SCHEMBL9901980 | 0.71 | BDKRB2 (0.35) | — | |
| SCHEMBL3790911 | 0.70 | MYC (0.33) | ALDH1A1HPGDABCG2 | |
| SCHEMBL2656551 | 0.70 | AR (0.40) | ARALDH1A1HPGD | |
| SCHEMBL31200955 | 0.69 | TSHR (0.40) | TSHRARALDH1A1HPGD | |
| SCHEMBL1452840 | 0.69 | HTT (0.38) | TSHRALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775702-B1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-5935952-A | ANTIBACTERIAL AGENT | TOYAMA CHEMICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0775702-A1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 1997-05-28 | — | — | EP | disclosed |