SCHEMBL7012297

SCHEMBL7012297

CC(=O)NCC1CC1c1cccc2ccc3c(c12)CCCO3

nearest known ligand 0.62

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 19/20 0.62
MTNR1B P49286 18/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7012295 1.00 MTNR1A (0.62) MTNR1AMTNR1B
SCHEMBL6681135 0.87 MTNR1B (0.67) MTNR1AMTNR1B
SCHEMBL6681132 0.87 MTNR1B (0.67) MTNR1AMTNR1B
SCHEMBL7699489 0.79 MTNR1B (0.78) MTNR1AMTNR1B
SCHEMBL6676672 0.79 MTNR1B (0.78) MTNR1AMTNR1B
SCHEMBL6676675 0.79 MTNR1B (0.78) MTNR1AMTNR1B
SCHEMBL1387212 0.77 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL7228199 0.77 MTNR1B (0.45) MTNR1AMTNR1B
SCHEMBL7009759 0.77 MTNR1B (0.45) MTNR1AMTNR1B
SCHEMBL6677570 0.76 MTNR1B (0.87) MTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6583319-B1 Treating or preventing melatoninergic disorders LES LABORATOIRES SERVIER (FR) 2003-06-24 US disclosed
EP-0994102-B1 Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them SERVIER LAB (FR) 2003-03-19 EP disclosed
EP-0994102-A1 Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 2000-04-19 EP disclosed