SCHEMBL70127

SCHEMBL70127

O=C(O)[C@@H]1CCC[C@H](C(=O)O)O1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.42
TFPI2 P48307 3/20 0.42
PMP22 Q01453 3/20 0.42
TSHR P16473 3/20 0.42
GMNN O75496 2/20 0.42
TP53 P04637 2/20 0.42
NFKB1 P19838 2/20 0.42
THPO P40225 2/20 0.42
KDM4E B2RXH2 1/20 0.42
SUCNR1 Q9BXA5 1/20 0.38
PPP1CA P62136 1/20 0.35
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
PEPD P12955 1/20 0.33
MAPK1 P28482 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
CYP2C19 P33261 1/20 0.32
STAT6 P42226 1/20 0.32
HIF1A Q16665 1/20 0.32
NPC1 O15118 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10669324 1.00 LMNA (0.42) LMNATFPI2PMP22TSHRGMNN
SCHEMBL68843 0.88 LMNA (0.46) LMNATFPI2PMP22TSHRGMNN
SCHEMBL38319 0.88 LMNA (0.46) LMNATFPI2PMP22TSHRGMNN
SCHEMBL25659464 0.82 FFAR3 (0.35) LMNATFPI2PMP22TSHRGMNN
SCHEMBL25659040 0.82 KDM4E (0.31) LMNATFPI2PMP22TSHRGMNN
SCHEMBL16841846 0.76 GMNN (0.37) LMNATFPI2PMP22TSHRGMNN
SCHEMBL9601533 0.74 KDM4E (0.36) LMNATFPI2PMP22TSHRGMNN
SCHEMBL20247476 0.72 KDM4E (0.34) LMNATFPI2PMP22TSHRGMNN
SCHEMBL7838127 0.72
SCHEMBL7826434 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
US-4158635-A Detergent formulations containing tetrahydropyran or 1,4-dioxane polycarboxylates and method for using same MONSANTO COMPANY (US) 1979-06-19 US disclosed
US-4134902-A DETERGENT BUILDERS, CALCIUM AND MAGNESIUM SEQUESTRANTS, SCALE DISSOLVERS MONSANTO COMPANY (US) 1979-01-16 US disclosed
US-4102903-A DETERGENTS BUILDERS, SEQUESTERING AGENTS MONSANTO COMPANY (US) 1978-07-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 LMNA 2207/4885TFPI2 4295/4885PMP22 2546/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.