Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | PPM1B | O75688 | 3/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
| ▸ | PPP1CC | P36873 | 3/20 | 0.35 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL68843 | 0.84 | LMNA (0.46) | KDM4EGMNNLMNAPMP22TFPI2 | |
| SCHEMBL38319 | 0.84 | LMNA (0.46) | KDM4EGMNNLMNAPMP22TFPI2 | |
| SCHEMBL21987133 | 0.82 | PPM1B (0.50) | KDM4EGMNNLMNAPMP22TFPI2 | |
| SCHEMBL8013452 | 0.82 | PPM1B (0.50) | KDM4EGMNNLMNAPMP22TFPI2 | |
| SCHEMBL15436927 | 0.76 | PPM1B (0.39) | TSHRPPM1BPTPN1PPP1CC | |
| SCHEMBL22942138 | 0.74 | PPM1B (0.38) | TSHRPPM1BPTPN1PPP1CC | |
| SCHEMBL10669324 | 0.74 | LMNA (0.42) | KDM4EGMNNLMNAPMP22TFPI2 | |
| SCHEMBL70127 | 0.74 | LMNA (0.42) | KDM4EGMNNLMNAPMP22TFPI2 | |
| SCHEMBL16841846 | 0.73 | GMNN (0.37) | KDM4EGMNNLMNAPMP22TFPI2 | |
| SCHEMBL25659463 | 0.73 | FFAR3 (0.38) | KDM4EGMNNLMNAPMP22TFPI2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0309544-B1 | PSYCHOTROPIC BICYCLIC IMIDES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-02-10 | — | — | EP | disclosed |
| EP-0309544-A1 | PSYCHOTROPIC BICYCLIC IMIDES. | AMERICAN HOME PROD (US) | 1989-04-05 | — | — | EP | disclosed |
| WO-1988007530-A1 | PSYCHOTROPIC BICYCLIC IMIDES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-10-06 | — | — | WO | disclosed |
| US-4748240-A | Psychotropic bicyclic imides | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-05-31 | — | — | US | disclosed |
| US-4216215-A | 7[(Furanyl-2-acetamido)-2-acetamido]cephalosporin derivatives | PFIZER INC. (US) | 1980-08-05 | — | — | US | disclosed |
| US-4137312-A | Epoxy substituted cephalosporin derivatives | PFIZER INC. (US) | 1979-01-30 | — | — | US | disclosed |