Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | STS | P08842 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | PREP | P48147 | 2/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367008 | 0.88 | PREP (0.48) | SMN1; SMN2NPC1RAB9AHTTGAA | |
| SCHEMBL7382762 | 0.86 | PREP (0.48) | SMN1; SMN2NPC1RAB9AHTTALDH1A1 | |
| SCHEMBL1938768 | 0.82 | HTT (0.64) | SMN1; SMN2NPC1RAB9AHTTCYP2C19 | |
| SCHEMBL205216 | 0.80 | SMN1; SMN2 (1.00) | SMN1; SMN2NPC1RAB9AHTTCYP2C19 | |
| SCHEMBL9052626 | 0.79 | SMN1; SMN2 (0.59) | SMN1; SMN2NPC1RAB9AHTTCYP2C19 | |
| SCHEMBL4031374 | 0.79 | FKBP1A (0.52) | ALDH1A1PREP | |
| SCHEMBL1241067 | 0.79 | KDM4E (0.69) | SMN1; SMN2NPC1RAB9AHTTSTS | |
| SCHEMBL5225678 | 0.79 | BCL9 (0.44) | SMN1; SMN2RAB9AHTTALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL3097843 | 0.78 | SMN1; SMN2 (0.97) | SMN1; SMN2NPC1RAB9AHTTCYP2C19 | |
| SCHEMBL20782479 | 0.78 | KDM4E (0.58) | SMN1; SMN2NPC1RAB9AHTTSTS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305308-A1 | AMINOPIPERIDINE QUINOLINES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 2003-05-02 | — | — | EP | disclosed |
| WO-2002008224-A1 | AMINOPIPERIDINE QUINOLINES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-01-31 | — | — | WO | disclosed |