Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 7/20 | 0.52 |
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.52 |
| ▸ | PREP | P48147 | 2/20 | 0.48 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367008 | 0.84 | PREP (0.48) | FKBP1APREP | |
| SCHEMBL7382762 | 0.83 | PREP (0.48) | FKBP1APREPALDH1A1 | |
| SCHEMBL4033512 | 0.81 | TMEM97 (0.68) | FKBP1ATMEM97SIGMAR1PREPEPHX2 | |
| Water SCHEMBL27700641 | 0.80 | TMEM97 (0.67) | FKBP1ATMEM97SIGMAR1PREPEPHX2 | |
| Water SCHEMBL27740102 | 0.79 | TMEM97 (0.66) | FKBP1ATMEM97SIGMAR1PREPEPHX2 | |
| SCHEMBL7012823 | 0.79 | SMN1; SMN2 (0.65) | PREPALDH1A1 | |
| SCHEMBL4021824 | 0.78 | RIPK1 (0.56) | TMEM97SIGMAR1RIPK1EPHX2 | |
| SCHEMBL20522962 | 0.78 | KDM1A (0.53) | FKBP1APREPALDH1A1 | |
| SCHEMBL20528094 | 0.78 | KDM1A (0.53) | FKBP1APREPALDH1A1 | |
| SCHEMBL30511036 | 0.78 | KDM1A (0.53) | FKBP1APREPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1545525-A4 | RADIOLABELED NEUROKININ-1 RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2009-07-01 | — | — | EP | disclosed |
| EP-1119356-A4 | RADIOLABELED NEUROKININ-1 RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2008-01-09 | — | — | EP | disclosed |
| EP-1545525-A2 | RADIOLABELED NEUROKININ-1 RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004029024-A2 | RADIOLABELED NEUROKININ-1 RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2004-04-08 | — | — | WO | disclosed |
| EP-1119356-A1 | RADIOLABELED NEUROKININ-1 RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 2001-08-01 | — | — | EP | disclosed |
| WO-2000018403-A1 | RADIOLABELED NEUROKININ-1 RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2000-04-06 | — | — | WO | disclosed |