Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 13/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 12/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7013102 | 1.00 | MTNR1A (0.55) | MTNR1AMTNR1BSMN1; SMN2NPSR1CHRNA7 | |
| SCHEMBL7004406 | 0.79 | MTNR1A (0.49) | MTNR1AMTNR1BCHRNA7 | |
| SCHEMBL7013921 | 0.78 | MTNR1B (0.58) | MTNR1AMTNR1B | |
| SCHEMBL7013920 | 0.78 | MTNR1B (0.58) | MTNR1AMTNR1B | |
| SCHEMBL7008448 | 0.78 | MTNR1A (0.45) | MTNR1AMTNR1B | |
| SCHEMBL7238905 | 0.78 | MTNR1A (0.45) | MTNR1AMTNR1B | |
| SCHEMBL7238727 | 0.74 | MTNR1A (0.42) | MTNR1AMTNR1B | |
| SCHEMBL7238723 | 0.74 | MTNR1A (0.42) | MTNR1AMTNR1B | |
| SCHEMBL7016214 | 0.73 | MTNR1A (0.47) | MTNR1AMTNR1B | |
| SCHEMBL7009054 | 0.73 | MTNR1A (0.43) | MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6583319-B1 | Treating or preventing melatoninergic disorders | LES LABORATOIRES SERVIER (FR) | 2003-06-24 | — | — | US | disclosed |
| EP-0994102-B1 | Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-03-19 | — | — | EP | disclosed |
| EP-0994102-A1 | Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-04-19 | — | — | EP | disclosed |