Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 4/20 | 0.42 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.42 |
| ▸ | GSK3B | P49841 | 10/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7006682 | 0.89 | TOP2A (0.55) | TOP2ATOP2BGSK3BKCNH2POLB | |
| SCHEMBL7017683 | 0.84 | TOP2A (0.45) | TOP2ATOP2BGSK3BKCNH2POLB | |
| SCHEMBL7496537 | 0.81 | GSK3B (0.49) | TOP2ATOP2BGSK3BKCNH2POLB | |
| SCHEMBL7098947 | 0.81 | TOP2A (0.53) | TOP2ATOP2BGSK3BKCNH2POLB | |
| SCHEMBL7012074 | 0.80 | TOP2A (0.51) | TOP2ATOP2BGSK3BKCNH2POLB | |
| SCHEMBL7011702 | 0.78 | TOP2A (0.65) | TOP2ATOP2BGSK3BKCNH2POLB | |
| SCHEMBL7502021 | 0.78 | KCNH2 (0.40) | TOP2ATOP2BGSK3BKCNH2POLB | |
| SCHEMBL7010007 | 0.77 | TOP2A (0.46) | TOP2ATOP2BKCNH2POLB | |
| SCHEMBL7012229 | 0.76 | TOP2A (0.57) | TOP2ATOP2BGSK3BKCNH2POLB | |
| SCHEMBL7007585 | 0.74 | TOP2A (0.44) | TOP2ATOP2BGSK3BKCNH2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775702-B1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2003-07-23 | — | — | EP | claimed |