Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL751860 | 0.80 | EPHX1 (0.57) | RAB9AEPHX1EPHX2SMN1; SMN2NPC1 | |
| SCHEMBL15263046 | 0.79 | EPHX1 (0.83) | RAB9AEPHX1EPHX2SMN1; SMN2NPC1 | |
| SCHEMBL10825858 | 0.79 | EPHX1 (0.83) | RAB9AEPHX1EPHX2SMN1; SMN2NPC1 | |
| SCHEMBL2518709 | 0.78 | SMN1; SMN2 (0.65) | RAB9AEPHX1EPHX2SMN1; SMN2NPC1 | |
| SCHEMBL1921374 | 0.77 | GAA (0.56) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL746119 | 0.76 | ALDH1A1 (0.47) | RAB9AEPHX1EPHX2SMN1; SMN2NPC1 | |
| SCHEMBL6756210 | 0.76 | HPGD (0.45) | RAB9ANPC1KMT2AMEN1GAA | |
| SCHEMBL6757892 | 0.76 | HPGD (0.49) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL6282431 | 0.75 | HPGD (0.51) | RAB9AEPHX1EPHX2SMN1; SMN2NPC1 | |
| SCHEMBL5469269 | 0.75 | EPHX1 (0.75) | RAB9AEPHX1EPHX2SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889034-B1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-6011039-A | USEFUL AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS; TREATING HYPERPHAGIA, OBESITY OR DIABETES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0889034-A1 | AMINOPYRIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-01-07 | — | — | EP | disclosed |