Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.42 |
| ▸ | TOP2A | P11388 | 12/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 12/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | EDNRA | P25101 | 1/20 | 0.37 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7009246 | 0.92 | DPP4 (0.49) | DPP4TOP2ATOP2BLMNACYP2C9 | |
| SCHEMBL7014330 | 0.86 | DPP4 (0.41) | DPP4TOP2ATOP2BLMNACYP2C9 | |
| SCHEMBL7011800 | 0.82 | KDM4E (0.47) | TOP2ATOP2BLMNACYP2C9KDM4E | |
| SCHEMBL7009304 | 0.81 | TOP2A (0.50) | TOP2ATOP2BLMNACYP2C9KDM4E | |
| SCHEMBL7014612 | 0.81 | TOP2A (0.50) | TOP2ATOP2BKDM4EALDH1A1HPGD | |
| SCHEMBL7008502 | 0.81 | TOP2A (0.61) | TOP2ATOP2BLMNACYP2C9KDM4E | |
| SCHEMBL7011864 | 0.81 | LMNA (0.58) | LMNACYP2C9KDM4EALDH1A1CYP1A2 | |
| SCHEMBL7010109 | 0.81 | LMNA (0.46) | DPP4TOP2ATOP2BLMNACYP2C9 | |
| SCHEMBL7007009 | 0.80 | LMNA (0.47) | DPP4TOP2ATOP2BLMNACYP2C9 | |
| SCHEMBL7015378 | 0.80 | CAPN1 (0.45) | TOP2ATOP2BLMNACYP2C9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775702-B1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-5935952-A | ANTIBACTERIAL AGENT | TOYAMA CHEMICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0775702-A1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 1997-05-28 | — | — | EP | disclosed |