Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 3/20 | 0.45 |
| ▸ | TOP2A | P11388 | 4/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7007009 | 0.94 | LMNA (0.47) | CAPN1TOP2ATOP2BLMNAKDM4E | |
| SCHEMBL7010437 | 0.86 | EPHA2 (0.54) | TOP2ATOP2BLMNAKDM4EALDH1A1 | |
| SCHEMBL7012905 | 0.86 | LMNA (0.45) | CAPN1TOP2ATOP2BLMNAKDM4E | |
| SCHEMBL7010843 | 0.84 | EPHA2 (0.37) | TOP2ATOP2BLMNAKDM4EALDH1A1 | |
| SCHEMBL7009246 | 0.82 | DPP4 (0.49) | TOP2ATOP2BLMNAKDM4EALDH1A1 | |
| SCHEMBL7010109 | 0.82 | LMNA (0.46) | TOP2ATOP2BLMNAKDM4EALDH1A1 | |
| SCHEMBL7011864 | 0.82 | LMNA (0.58) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7008289 | 0.82 | ALDH1A1 (0.50) | CAPN1TOP2ATOP2BLMNAKDM4E | |
| SCHEMBL7010570 | 0.82 | TOP2A (0.48) | CAPN1TOP2ATOP2BLMNAKDM4E | |
| SCHEMBL7010315 | 0.81 | TOP2A (0.57) | CAPN1TOP2ATOP2BLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775702-B1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-5935952-A | ANTIBACTERIAL AGENT | TOYAMA CHEMICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0775702-A1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 1997-05-28 | — | — | EP | disclosed |