Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7005055 | 0.89 | HTR1F (0.48) | HTR1FSLC6A4KDM4ELMNAPOLB | |
| SCHEMBL30909106 | 0.89 | HTR1F (0.48) | HTR1FSLC6A4KDM4ELMNAPOLB | |
| SCHEMBL30909164 | 0.86 | HTR1F (0.47) | HTR1FSLC6A4KDM4ELMNAPOLB | |
| SCHEMBL7009335 | 0.86 | HTR1F (0.47) | HTR1FSLC6A4KDM4ELMNAPOLB | |
| SCHEMBL7013302 | 0.80 | HTR1F (0.46) | HTR1FSLC6A4KDM4ELMNAPOLB | |
| SCHEMBL30909216 | 0.80 | HTR1F (0.46) | HTR1FSLC6A4KDM4ELMNAPOLB | |
| SCHEMBL7012941 | 0.78 | HTR1F (0.54) | HTR1FHTR1AHTR6 | |
| SCHEMBL7010491 | 0.77 | HTR1F (0.49) | HTR1FSLC6A4KDM4ELMNAPOLB | |
| SCHEMBL7095378 | 0.76 | HTR1F (0.54) | HTR1FSLC6A4KDM4ELMNAHTR1A | |
| SCHEMBL7007191 | 0.75 | HTR1F (0.48) | HTR1FSLC6A4KDM4ELMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0916670-B1 | Pyrrolo-(3,2-b) pyridines and their use as 5-HT1F agonists | LILLY CO ELI (US) | 2003-05-14 | — | — | EP | disclosed |
| EP-0916670-A2 | Pyrrolo-(3,2-b) pyridines and their use as 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1999-05-19 | — | — | EP | disclosed |
| US-5905084-A | 5-SUBSTITUTED-3-(PIPERIDIN-4-YL)- AND -3-(1,2,3,6-TETRAHYDROPYRIDIN-4-YL)PYRROLO(3,2-B)PYRIDINES; SIDE EFFECT REDUCTION; NERVOUS SYTEM AND PSYCHOLOGICAL DISORDERS | ELI LILLY AND COMPANY (US) | 1999-05-18 | — | — | US | disclosed |