Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5774764 | 0.80 | FAAH (0.60) | FAAHKCNH2 | |
| SCHEMBL5774252 | 0.78 | KCNH2 (0.40) | FAAHKCNH2 | |
| SCHEMBL14573150 | 0.77 | KCNH2 (0.51) | KCNH2 | |
| SCHEMBL5764918 | 0.76 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL7014183 | 0.72 | PIK3CA (0.35) | FAAHKCNH2 | |
| Oxalic Acid SCHEMBL5255846 | 0.71 | POLB (0.40) | KCNH2 | |
| SCHEMBL6669043 | 0.71 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL6667359 | 0.70 | KCNH2 (0.52) | KCNH2 | |
| SCHEMBL590199 | 0.69 | MAP4K4 (0.44) | KCNH2 | |
| Fumaric Acid SCHEMBL5264306 | 0.69 | POLB (0.37) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343780-A1 | PIPERAZINE DERIVATIVES FOR TREATMENT OF BACTERIAL INFECTIONS | SMITHKLINE BEECHAM PLC (GB) | 2003-09-17 | — | — | EP | claimed |
| WO-2002050061-A1 | PIPERAZINE DERIVATIVES FOR TREATMENT OF BACTERIAL INFECTIONS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-06-27 | — | — | WO | claimed |