Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 11/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 11/20 | 0.41 |
| ▸ | DPP4 | P27487 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7010564 | 0.89 | TOP2A (0.50) | TOP2ATOP2BDPP4KDM4EALDH1A1 | |
| SCHEMBL7014330 | 0.86 | DPP4 (0.41) | TOP2ATOP2BDPP4KDM4EALDH1A1 | |
| SCHEMBL7006766 | 0.83 | LMNA (0.53) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL7010392 | 0.83 | KDM4E (0.48) | TOP2ATOP2BKDM4EALDH1A1HPGD | |
| SCHEMBL8319527 | 0.82 | TOP2A (0.46) | TOP2ATOP2BKDM4EALDH1A1HPGD | |
| SCHEMBL8319531 | 0.82 | TOP2A (0.46) | TOP2ATOP2BKDM4EALDH1A1HPGD | |
| SCHEMBL7012437 | 0.82 | KDM4E (0.40) | TOP2ATOP2BKDM4EALDH1A1HPGD | |
| SCHEMBL8327077 | 0.82 | KDM4E (0.40) | TOP2ATOP2BKDM4EALDH1A1HPGD | |
| SCHEMBL7013980 | 0.81 | TOP2A (0.46) | TOP2ATOP2BKDM4EALDH1A1HPGD | |
| SCHEMBL8322689 | 0.81 | TOP2A (0.46) | TOP2ATOP2BKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775702-B1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-5935952-A | ANTIBACTERIAL AGENT | TOYAMA CHEMICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |