Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | EDNRA | P25101 | 1/20 | 0.44 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TOP1 | P11387 | 6/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7006766 | 0.93 | LMNA (0.53) | KDM4EALDH1A1LMNACYP2C9ATP6V1B2 | |
| SCHEMBL7010109 | 0.87 | LMNA (0.46) | KDM4EALDH1A1LMNACYP2C9ATP6V1B2 | |
| SCHEMBL7010564 | 0.84 | TOP2A (0.50) | KDM4EALDH1A1LMNAABCC4HPGD | |
| SCHEMBL7012905 | 0.83 | LMNA (0.45) | KDM4EALDH1A1LMNACYP2C9ATP6V1B2 | |
| SCHEMBL7013772 | 0.83 | LMNA (0.52) | KDM4EALDH1A1LMNACYP2C9ATP6V1B2 | |
| SCHEMBL7014272 | 0.83 | TOP2A (0.41) | KDM4EALDH1A1HPGDTOP2ATOP2B | |
| SCHEMBL7008660 | 0.83 | EPHA2 (0.54) | KDM4EALDH1A1LMNACYP2C9ATP6V1B2 | |
| SCHEMBL7016362 | 0.81 | KDM4E (0.56) | KDM4EALDH1A1DRD3MEN1KMT2A | |
| SCHEMBL10928284 | 0.81 | KDM4E (0.47) | KDM4EALDH1A1LMNACYP2C9ATP6V1B2 | |
| SCHEMBL7010024 | 0.81 | ALDH1A1 (0.60) | KDM4EALDH1A1LMNADRD3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775702-B1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-5935952-A | ANTIBACTERIAL AGENT | TOYAMA CHEMICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0775702-A1 | NOVEL QUINOLONE- OR NAPHTHYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 1997-05-28 | — | — | EP | disclosed |