Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.60 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | F7 | P08709 | 1/20 | 0.50 |
| ▸ | F3 | P13726 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | F11 | P03951 | 1/20 | 0.42 |
| ▸ | PYGL | P06737 | 2/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30222912 | 0.81 | SIRT1 (0.58) | SIRT1LOXL2SMN1; SMN2F7F3 | |
| SCHEMBL7014368 | 0.80 | LOXL2 (0.57) | SIRT1LOXL2SMN1; SMN2F7F3 | |
| SCHEMBL1500849 | 0.79 | LOXL2 (0.64) | SIRT1LOXL2SMN1; SMN2F7F3 | |
| SCHEMBL10593440 | 0.78 | SIRT1 (0.56) | SIRT1LOXL2SMN1; SMN2F7F3 | |
| SCHEMBL866136 | 0.78 | LOXL2 (0.72) | SIRT1LOXL2SMN1; SMN2F7F3 | |
| SCHEMBL5097277 | 0.76 | SIRT1 (0.74) | SIRT1LOXL2SMN1; SMN2F7F3 | |
| SCHEMBL4740651 | 0.75 | LOXL2 (0.68) | SIRT1LOXL2SMN1; SMN2F7F3 | |
| SCHEMBL13805336 | 0.72 | SIRT1 (0.52) | SIRT1LOXL2SMN1; SMN2F7F3 | |
| SCHEMBL2056276 | 0.72 | LOXL2 (0.68) | SIRT1LOXL2SMN1; SMN2F7F3 | |
| SCHEMBL4153224 | 0.72 | LOXL2 (1.00) | SIRT1LOXL2SMN1; SMN2F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030187023-A1 | Sulfone derivatives, process for their production and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-10-02 | — | — | US | disclosed |
| EP-1302462-A1 | SULFONE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2003-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187023-A1 | Sulfone derivatives, process for their production and use thereof | SULT1E1, RRS1, SHH | SIRT1 2618/4885LOXL2 2384/4885SMN1; SMN2 3830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.