Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | ATM | Q13315 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | ERN1 | O75460 | 5/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.50 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14628717 | 0.91 | ALDH1A1 (0.53) | ALDH1A1KDM4EHSD17B10ATMHPGD | |
| SCHEMBL9816120 | 0.91 | ERN1 (0.49) | ALDH1A1KDM4EHSD17B10ATMHPGD | |
| SCHEMBL20628600 | 0.90 | ERN1 (0.48) | ALDH1A1KDM4EHSD17B10ATMHPGD | |
| SCHEMBL28984395 | 0.86 | KDM4E (0.59) | ALDH1A1KDM4EHSD17B10ATMHPGD | |
| SCHEMBL17747083 | 0.85 | ALDH1A1 (0.58) | ALDH1A1KDM4EHSD17B10ATMHPGD | |
| SCHEMBL5485053 | 0.84 | KDM4E (0.53) | ALDH1A1KDM4EHSD17B10ATMHPGD | |
| SCHEMBL25106844 | 0.82 | CYP46A1 (0.50) | ALDH1A1KDM4EHSD17B10ATMHPGD | |
| SCHEMBL8702460 | 0.82 | ALDH1A1 (0.57) | ALDH1A1KDM4EHSD17B10ATMHPGD | |
| SCHEMBL1485297 | 0.82 | XDH (0.65) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| SCHEMBL18373091 | 0.82 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDMAPTERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115806568-A | Method for constructing heteroatom substituted xanthene derivative through palladium-catalyzed cross coupling and application | 华东师范大学 | 2023-03-17 | — | — | CN | disclosed |
| EP-0815859-B1 | INTIMAL THICKENING INHIBITORS | TAIHO PHARMACEUTICAL CO LTD (JP) | 2003-06-18 | — | — | EP | disclosed |
| US-5977130-A | CARDIOVASCULAR DISORDERS | TAIHO PHARMEUTICAL CO., LTD. (JP) | 1999-11-02 | — | — | US | disclosed |
| EP-0815859-A1 | INTIMAL THICKENING INHIBITORS | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1998-01-07 | — | — | EP | disclosed |