Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 15/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.49 |
| ▸ | HTR1A | P08908 | 4/20 | 0.36 |
| ▸ | HTR1D | P28221 | 4/20 | 0.36 |
| ▸ | HTR1B | P28222 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7019670 | 0.84 | MTNR1A (0.70) | MTNR1AMTNR1B | |
| SCHEMBL7104463 | 0.84 | MTNR1A (0.70) | MTNR1AMTNR1B | |
| SCHEMBL7024587 | 0.82 | MTNR1A (0.55) | MTNR1AMTNR1BHTR1AHTR1DHTR1B | |
| SCHEMBL7018441 | 0.80 | MTNR1A (0.71) | MTNR1AMTNR1B | |
| SCHEMBL7099154 | 0.79 | MTNR1A (0.55) | MTNR1AMTNR1BMAPT | |
| SCHEMBL7021360 | 0.77 | NQO2 (0.52) | MTNR1AMTNR1BMAPT | |
| SCHEMBL7024468 | 0.74 | MTNR1A (0.46) | MTNR1AMTNR1BMAPT | |
| SCHEMBL9120459 | 0.71 | MTNR1A (0.76) | MTNR1AMTNR1B | |
| SCHEMBL9121553 | 0.70 | MTNR1A (0.74) | MTNR1AMTNR1B | |
| SCHEMBL7018052 | 0.69 | MTNR1A (0.64) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1057826-B1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-04-16 | — | — | EP | disclosed |
| US-6310074-B1 | TREATING MELATONINERGIC DISORDERS | ADIR ET COMPAGNIE (FR) | 2001-10-30 | — | — | US | disclosed |
| EP-1057826-A1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-12-06 | — | — | EP | disclosed |