Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 17/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.55 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | HTR1D | P28221 | 2/20 | 0.39 |
| ▸ | HTR1B | P28222 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7019670 | 0.89 | MTNR1A (0.70) | MTNR1AMTNR1B | |
| SCHEMBL7018441 | 0.84 | MTNR1A (0.71) | MTNR1AMTNR1B | |
| SCHEMBL7021129 | 0.83 | MTNR1A (0.78) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7014496 | 0.82 | MTNR1A (0.49) | MTNR1AMTNR1BHTR1AHTR1DHTR1B | |
| SCHEMBL7021360 | 0.81 | NQO2 (0.52) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7017862 | 0.79 | MTNR1A (0.59) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7025435 | 0.77 | SPR (0.58) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL9121553 | 0.75 | MTNR1A (0.74) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7024468 | 0.75 | MTNR1A (0.46) | MTNR1AMTNR1B | |
| SCHEMBL14521480 | 0.73 | IDO1 (0.61) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1057826-B1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-04-16 | — | — | EP | disclosed |
| US-6310074-B1 | TREATING MELATONINERGIC DISORDERS | ADIR ET COMPAGNIE (FR) | 2001-10-30 | — | — | US | disclosed |
| EP-1057826-A1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-12-06 | — | — | EP | disclosed |