Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PRKCI | P41743 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8539802 | 0.71 | SLC2A1 (0.32) | SLC2A1ALDH1A1PARP1PRKCIPDE4B | |
| SCHEMBL5534611 | 0.64 | KMT2A (0.33) | — | |
| SCHEMBL767200 | 0.62 | — | — | |
| SCHEMBL1064468 | 0.58 | SLC2A1 (0.36) | SLC2A1ALDH1A1PARP1PRKCIPDE4B | |
| SCHEMBL8885482 | 0.58 | SLC2A1 (0.36) | SLC2A1ALDH1A1PARP1PRKCIPDE4B | |
| SCHEMBL9236847 | 0.57 | SLC2A1 (0.32) | SLC2A1ALDH1A1PARP1PRKCIPDE4B | |
| SCHEMBL9232389 | 0.55 | SLC2A1 (0.33) | SLC2A1ALDH1A1PARP1PRKCIPDE4B | |
| SCHEMBL16416075 | 0.54 | SLC2A1 (0.36) | SLC2A1ALDH1A1PARP1PRKCIPDE4B | |
| SCHEMBL994116 | 0.53 | ALDH1A1 (0.46) | SLC2A1ALDH1A1PARP1PRKCIPDE4B | |
| SCHEMBL15522163 | 0.53 | CDC25B (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | claimed |
| EP-0733633-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |