Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1064468 | 0.83 | SLC2A1 (0.36) | SLC2A1ALDH1A1PARP1PRKCIPDE4B | |
| SCHEMBL1437770 | 0.71 | — | — | |
| SCHEMBL5110684 | 0.67 | MAPT (0.38) | PARP1 | |
| SCHEMBL10766157 | 0.64 | PNP (0.38) | — | |
| SCHEMBL7014615 | 0.58 | SLC2A1 (0.32) | SLC2A1ALDH1A1PARP1PRKCIPDE4B | |
| SCHEMBL4564464 | 0.56 | HSD17B10 (0.50) | SLC2A1ALDH1A1PARP1PRKCIPDE4B | |
| SCHEMBL2733971 | 0.55 | GDA (0.34) | XDH | |
| SCHEMBL28051130 | 0.55 | SLC2A1 (0.33) | SLC2A1ALDH1A1PARP1PRKCIPDE4B | |
| SCHEMBL9521932 | 0.55 | — | — | |
| SCHEMBL12118183 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5631259-A | PURINE BASE DERIVATIVES FOR NUCLEOSIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-20 | — | — | US | disclosed |
| EP-0521463-A2 | Substituted cyclic cycloalkyltriols, process, intermediates for their preparation and their use as antiviral and antiparasitic agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-01-07 | — | — | EP | disclosed |