Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.48 |
| ▸ | NAMPT | P43490 | 5/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.47 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.45 |
| ▸ | ITGAV | P06756 | 1/20 | 0.45 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.45 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7382386 | 0.88 | PPARG (0.63) | KDRPPARGNPC1RAB9AROCK2 | |
| SCHEMBL7856448 | 0.82 | PPARG (0.68) | KDRPPARGMAPTNPC1RAB9A | |
| SCHEMBL8500095 | 0.81 | PPARG (0.59) | KDRPPARGMAPTNPC1RAB9A | |
| SCHEMBL7372561 | 0.78 | KCNK3 (0.56) | KDRPPARGMAPTNPC1RAB9A | |
| SCHEMBL2833493 | 0.77 | ITGB3 (0.51) | KDRMAPTNPC1RAB9AROCK2 | |
| SCHEMBL7372874 | 0.76 | NAMPT (0.57) | MAPTNPC1RAB9AROCK2NAMPT | |
| SCHEMBL8500098 | 0.76 | PPARG (0.50) | KDRPPARGNPC1RAB9AITGB3 | |
| SCHEMBL2837406 | 0.74 | ITGB3 (0.54) | KDRMAPTNPC1RAB9AROCK2 | |
| SCHEMBL7372795 | 0.73 | PPARG (0.54) | PPARGNPC1RAB9AROCK2ITGB3 | |
| SCHEMBL7453653 | 0.73 | PPARG (0.54) | PPARGNPC1RAB9AROCK2ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1282602-A1 | PROPANOIC ACID DERIVATIVES AS INTEGRIN RECEPTOR ANTAGONISTS | Pharmacia Italia S.p.A. (IT) | 2003-02-12 | — | — | EP | claimed |
| WO-2001087840-A1 | PROPANOIC ACID DERIVATIVES AS INTEGRIN RECEPTOR ANTAGONISTS | PHARMACIA ITALIA S.P.A. (IT) | 2001-11-22 | — | — | WO | claimed |