SCHEMBL70150

SCHEMBL70150

Oc1cc(O)c(I)cc1I

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.42
ALB P02768 1/20 0.33
HSP90AA1 P07900 2/20 0.32
BACE1 P56817 1/20 0.31
MEN1 O00255 2/20 0.31
LMNA P02545 2/20 0.31
HTT P42858 2/20 0.31
KMT2A Q03164 2/20 0.31
KDM4E B2RXH2 1/20 0.30
USP2 O75604 1/20 0.30
ALDH1A1 P00352 1/20 0.30
EGFR P00533 1/20 0.30
ERBB2 P04626 1/20 0.30
TP53 P04637 1/20 0.30
LCK P06239 1/20 0.30
FYN P06241 1/20 0.30
ADORA3 P0DMS8 1/20 0.30
HPGD P15428 1/20 0.30
ALOX15 P16050 1/20 0.30
SLC6A2 P23975 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4047179 0.89 TTR (0.40) TTRALB
SCHEMBL357190 0.88 TTR (0.44) TTRALBBACE1MEN1LMNA
SCHEMBL7871735 0.78 MAPT (0.42) TTRALBMEN1LMNAHTT
SCHEMBL7525100 0.78 CA1 (0.37) TTRALBMEN1KMT2AKDM4E
SCHEMBL12658291 0.78 KDM4E (0.48) TTRALBKMT2AKDM4EALDH1A1
SCHEMBL22560903 0.78 HSD17B10 (0.46) TTRHSP90AA1BACE1MEN1LMNA
SCHEMBL5785240 0.74 HSD17B10 (0.55) TTRHSP90AA1MEN1LMNAHTT
SCHEMBL18894055 0.74 CA9 (0.36) TTRHSP90AA1KDM4EHSD17B10TDP1
SCHEMBL3892350 0.74 MAPT (0.43) TTRALBMEN1LMNAHTT
SCHEMBL21614376 0.73 ACHE (0.43) BACE1LMNAHTTKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007089785-A2 APPARATUS AND SEMICONDUCTOR CO-CRYSTAL UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2007-08-09 WO claimed
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
WO-2007089785-A2 APPARATUS AND SEMICONDUCTOR CO-CRYSTAL UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2007-08-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 TTR 3513/4885ALB 2875/4885HSP90AA1 106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.