Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL9715828 | 0.86 | — | — | |
| Formaldehyde SCHEMBL27537805 | 0.86 | ALDH1A1 (0.35) | CES2CES1ALDH1A1 | |
| SCHEMBL115822 | 0.86 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL119021 | 0.86 | — | — | |
| SCHEMBL2499145 | 0.86 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL304571 | 0.86 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL26890 | 0.86 | — | — | |
| Methacrylic Acid SCHEMBL28186426 | 0.84 | GRIK1 (0.35) | CES2CES1GRIK1EPHX1GRIK2 | |
| Formic Acid SCHEMBL6262603 | 0.84 | ADH1A (0.33) | CES2CES1ALDH1A1 | |
| Formic Acid SCHEMBL6264008 | 0.84 | ADH1A (0.33) | CES2CES1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0816393-B1 | Curing agent for epoxy resins | VANTICO AG (CH) | 2003-11-19 | — | — | EP | claimed |
| EP-0816393-A2 | Curing agent for epoxy resins | Ciba SC Holding AG (CH) | 1998-01-07 | — | — | EP | claimed |
| US-10513573-B2 | Process for producing silver nanowires and agent for controlling growth of silver nanowires | SEIKO PMC CORPORATION (JP) | 2019-12-24 | — | — | US | disclosed |
| US-10293573-B2 | Micro flow channel chip and method for producing flow channel chip | SUMITOMO BAKELITE COMPANY LIMITED (JP) | 2019-05-21 | — | — | US | disclosed |
| US-20170354971-A1 | FLOW CHANNEL DEVICE | SUMITOMO BAKELITE CO., LTD. (JP) | 2017-12-14 | — | — | US | disclosed |
| US-20170203537-A1 | MICRO FLOW CHANNEL CHIP AND METHOD FOR PRODUCING FLOW CHANNEL CHIP | SUMITOMO BAKELITE CO., LTD. (JP) | 2017-07-20 | — | — | US | disclosed |
| US-20170174804-A1 | Process for Producing Silver Nanowires and Agent for Controlling Growth of Silver Nanowires | CHEMIPAZ CORPORATION (JP) | 2017-06-22 | — | — | US | disclosed |
| US-9630250-B2 | Process for producing silver nanowires and agent for controlling growth of silver nanowires | SEIKO PMC CORPORATION (JP) | 2017-04-25 | — | — | US | disclosed |
| US-9399725-B2 | Temporary bonding adhesive for a semiconductor wafer and method for manufacturing a semiconductor device using the same | SUMITOMO BAKELITE CO., LTD. (JP) | 2016-07-26 | — | — | US | disclosed |
| US-9051452-B2 | Polymer compositions for temporary bonding | PROMERUS, LLC (US) | 2015-06-09 | — | — | US | disclosed |
| EP-2351804-B1 | USE OF A RESIN COMPOSITION AS A TEMPORARILY FIXING AGENT FOR SEMICONDUCTOR WAFER, AND PROCESS FOR PRODUCTION OF SEMICONDUCTOR DEVICE USING SAME | SUMITOMO BAKELITE CO (JP) | 2014-12-10 | — | — | EP | disclosed |
| US-20060246232-A1 | Optical film, polarizing plate and in-plane switching mode liquid crystal display | KONICA MINOLTA OPTO, INC. | 2006-11-02 | — | — | US | disclosed |
| EP-0816393-B1 | Curing agent for epoxy resins | VANTICO AG (CH) | 2003-11-19 | — | — | EP | disclosed |
| EP-1163280-B1 | EPOXY RESIN COMPOSITIONS HAVING A LONG SHELF LIFE | VANTICO AG (CH) | 2002-11-06 | — | — | EP | disclosed |
| EP-0853099-A2 | Thixotropic agent for cycloolefins | Ciba SC Holding AG (CH) | 1998-07-15 | — | — | EP | disclosed |
| EP-0816393-A2 | Curing agent for epoxy resins | Ciba SC Holding AG (CH) | 1998-01-07 | — | — | EP | disclosed |
| US-4594406-A | From a phenyl, naphthyl or cyclohexyl dicarboxylic acid | EASTMAN KODAK COMPANY (US) | 1986-06-10 | — | — | US | disclosed |
| US-4521585-A | USING AMINE POLYMERIZATION CATALYST | EASTMAN KODAK COMPANY (US) | 1985-06-04 | — | — | US | disclosed |
| US-4353831-A | Process for making alkylene carbonates | THE DOW CHEMICAL COMPANY (US) | 1982-10-12 | — | — | US | disclosed |
| US-4344881-A | Process for making alkylene carbonates | THE DOW CHEMICAL COMPANY (US) | 1982-08-17 | — | — | US | disclosed |