Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | RHOA | P61586 | 1/20 | 0.49 |
| ▸ | ANO1 | Q5XXA6 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1856914 | 0.83 | POLB (0.54) | NFKB1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL4099966 | 0.80 | RHOA (0.74) | NFKB1RHOANPC1RAB9AKMT2A | |
| SCHEMBL2124418 | 0.80 | NFKB1 (0.57) | NFKB1LMNARHOANPC1RAB9A | |
| SCHEMBL14536688 | 0.79 | NFKB1 (0.54) | NFKB1SCN9A | |
| SCHEMBL20511106 | 0.78 | RHOA (0.61) | NFKB1LMNARHOANPC1RAB9A | |
| SCHEMBL1552392 | 0.77 | RHOA (0.79) | NFKB1LMNARHOANPC1RAB9A | |
| SCHEMBL2355018 | 0.75 | SCN9A (0.62) | SCN9A | |
| SCHEMBL12852616 | 0.75 | LMNA (0.61) | LMNAANO1KMT2AGAAMEN1 | |
| SCHEMBL18232992 | 0.75 | LMNA (0.65) | LMNAANO1KMT2AGAAMEN1 | |
| SCHEMBL30422700 | 0.75 | NFKB1 (0.51) | NFKB1RHOANPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0969004-B1 | 2,4,6-Trianilino-1,3,5-triazine derivatives, their preparation and their use as sunscreens against UV-B sun radiations | 3V SIGMA SPA (IT) | 2003-12-10 | — | — | EP | disclosed |
| EP-0969004-A2 | 2,4,6-Trianilino-1,3,5-triazine derivatives, their preparation and their use as sunscreens against UV-B sun radiations | 3V SIGMA S.p.A (IT) | 2000-01-05 | — | — | EP | disclosed |