Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 4/20 | 0.37 |
| ▸ | HTR1A | P08908 | 3/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4275487 | 0.88 | SLC2A1 (0.48) | CCR8MEN1KMT2AGAASLC2A1 | |
| SCHEMBL5652075 | 0.78 | CCR8 (0.45) | CCR8MEN1KMT2ASLC2A1HTR2B | |
| SCHEMBL4275508 | 0.73 | KCNH2 (0.65) | CCR8SLC2A1KCNH2 | |
| SCHEMBL5778069 | 0.73 | MEN1 (0.38) | MEN1KMT2AGAASLC2A1HTR2B | |
| SCHEMBL6985392 | 0.72 | NCF1 (0.58) | MEN1KMT2AHTR2BHTR1ADRD2 | |
| SCHEMBL7017484 | 0.71 | CYP2D6 (0.48) | MEN1KMT2ASLC2A1HTR2BDRD2 | |
| SCHEMBL3690599 | 0.70 | KCNH2 (0.50) | CCR8MEN1KMT2ASLC2A1KCNH2 | |
| SCHEMBL6988402 | 0.69 | CYP2D6 (0.44) | MEN1KMT2ASLC2A1HTR2BDRD2 | |
| SCHEMBL13145896 | 0.69 | KCNH2 (0.48) | CCR8MEN1KMT2ASLC2A1HTR2B | |
| SCHEMBL7146164 | 0.68 | SLC2A1 (0.48) | MEN1KMT2ASLC2A1DRD2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305308-A1 | AMINOPIPERIDINE QUINOLINES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 2003-05-02 | — | — | EP | disclosed |
| WO-2002008224-A1 | AMINOPIPERIDINE QUINOLINES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-01-31 | — | — | WO | disclosed |