Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 7/20 | 0.38 |
| ▸ | HTR2B | P41595 | 6/20 | 0.38 |
| ▸ | HTR1A | P08908 | 4/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4275487 | 0.85 | SLC2A1 (0.48) | MEN1KMT2AGAADRD2HTR2B | |
| SCHEMBL5777778 | 0.84 | SLC2A1 (0.47) | MEN1KMT2ADRD2HTR2BHTR1A | |
| SCHEMBL3690604 | 0.77 | SLC2A1 (0.36) | MEN1KMT2ADRD2HTR2BHTR1A | |
| SCHEMBL7015177 | 0.73 | CCR8 (0.42) | MEN1KMT2AGAADRD2HTR2B | |
| SCHEMBL3698321 | 0.71 | HCRTR1 (0.35) | MEN1KMT2ADRD2HTR2BHTR1A | |
| SCHEMBL5760601 | 0.69 | RECQL (0.45) | MEN1KMT2ADRD2HTR2BHTR1A | |
| SCHEMBL4275508 | 0.69 | KCNH2 (0.65) | SLC2A1KCNH2 | |
| SCHEMBL5778699 | 0.69 | SLC2A1 (0.58) | MEN1KMT2ADRD2HTR2BHTR1A | |
| SCHEMBL5775396 | 0.69 | KCNH2 (0.49) | DRD2HTR1ADRD3SLC2A1HTR2A | |
| SCHEMBL5757154 | 0.68 | L3MBTL1 (0.54) | MEN1KMT2ADRD2HTR2BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305308-B1 | AMINOPIPERIDINE QUINOLINES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 2006-12-20 | — | — | EP | claimed |