SCHEMBL7015396

SCHEMBL7015396

Nc1ccc(Oc2ccc(-c3ccccc3)cc2)c(N)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.54
CYP1A2 P05177 2/20 0.54
CYP2C9 P11712 2/20 0.54
CYP2C19 P33261 2/20 0.54
NCOA1 Q15788 1/20 0.54
NCOA3 Q9Y6Q9 1/20 0.54
MAOA P21397 2/20 0.48
TAAR1 Q96RJ0 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
MAPT P10636 4/20 0.47
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
ALDH1A1 P00352 3/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
KDM4E B2RXH2 1/20 0.47
CYP2D6 P10635 1/20 0.47
HPGD P15428 1/20 0.47
LMNA P02545 2/20 0.45
HTT P42858 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29866044 1.00 CYP3A4 (0.54) CYP3A4CYP1A2CYP2C9CYP2C19NCOA1
SCHEMBL28806097 0.93 MAPT (0.53) CYP3A4CYP1A2CYP2C9CYP2C19NCOA1
SCHEMBL27741074 0.93 MAPT (0.53) CYP3A4CYP1A2CYP2C9CYP2C19NCOA1
SCHEMBL25135225 0.91 NCOA1 (0.57) CYP3A4CYP1A2CYP2C9CYP2C19NCOA1
SCHEMBL28417223 0.89 MAOA (0.63) CYP3A4CYP1A2CYP2C9CYP2C19NCOA1
SCHEMBL3114464 0.89 CYP1A2 (0.67) CYP3A4CYP1A2CYP2C9CYP2C19NCOA1
SCHEMBL29382755 0.89 CYP1A2 (0.67) CYP3A4CYP1A2CYP2C9CYP2C19NCOA1
Hydrochloric Acid SCHEMBL8642598 0.87 CYP1A2 (0.65) CYP3A4CYP1A2CYP2C9CYP2C19NCOA1
SCHEMBL7806773 0.87 MAPT (0.59) CYP3A4CYP1A2CYP2C9CYP2C19NCOA1
SCHEMBL3784764 0.86 CYP3A4 (0.59) CYP3A4CYP1A2CYP2C9CYP2C19NCOA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109928907-A One kind having excellent machining property and reactive diluent resistant to high temperature and preparation method thereof 上海交通大学 2019-06-25 CN claimed
EP-0122060-B1 MELT-FUSIBLE POLYIMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-11-07 EP claimed
US-4576857-A ETHER AMINES AND PYROMELLITIC ACID E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-03-18 US claimed
EP-0122060-A2 Melt-fusible polyimides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-10-17 EP claimed
CN-116426130-B Carbon nanohorn modified polyimide resin and application thereof 北京清大际光科技发展有限公司 2024-01-23 CN disclosed
CN-116426130-A Carbon nanohorn modified polyimide resin and application thereof 北京清大际光科技发展有限公司 2023-07-14 CN disclosed
CN-109928907-B Reactive diluent with excellent processability and high temperature resistance and preparation method thereof 上海交通大学 2022-08-16 CN disclosed
CN-108641082-B Thermosetting polyimide prepolymer and preparation method and application thereof 常州杰铭新材料科技有限公司 2020-08-25 CN disclosed
CN-111154101-A High-temperature-resistant ethynyl terminated polyimide material and preparation method thereof 神马实业股份有限公司 2020-05-15 CN disclosed
CN-109928907-A One kind having excellent machining property and reactive diluent resistant to high temperature and preparation method thereof 上海交通大学 2019-06-25 CN disclosed
EP-0682283-B1 Liquid crystal alignment film NISSAN CHEMICAL IND LTD (JP) 2003-01-15 EP disclosed
US-5608033-A POLYIMIDES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1997-03-04 US disclosed
EP-0682283-A1 Liquid crystal alignment film NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1995-11-15 EP disclosed
EP-0122060-B1 MELT-FUSIBLE POLYIMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-11-07 EP disclosed
US-4576857-A ETHER AMINES AND PYROMELLITIC ACID E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-03-18 US disclosed
US-4485140-A BINDERS FOR COMPOSITES IN AEROSPACE AND AUTOMOBILE INDUSTRIES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-11-27 US disclosed
EP-0122060-A2 Melt-fusible polyimides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-10-17 EP disclosed