SCHEMBL28806097

SCHEMBL28806097

Nc1ccc(Oc2ccc(-c3ccc(-c4ccc(-c5ccc(Oc6ccc(N)cc6N)cc5)cc4)cc3)cc2)c(N)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.53
ALDH1A1 P00352 8/20 0.53
MEN1 O00255 5/20 0.53
KMT2A Q03164 5/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
CYP1A2 P05177 2/20 0.53
CYP2C9 P11712 2/20 0.53
CYP2C19 P33261 2/20 0.53
KDM4E B2RXH2 2/20 0.53
CYP2D6 P10635 1/20 0.53
HPGD P15428 1/20 0.53
CYP3A4 P08684 3/20 0.47
TDP1 Q9NUW8 2/20 0.46
TSHR P16473 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.45
RAB9A P51151 1/20 0.45
GAA P10253 3/20 0.43
HTT P42858 2/20 0.43
ATM Q13315 2/20 0.43
TP53 P04637 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27741074 1.00 MAPT (0.53) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL7806773 0.94 MAPT (0.59) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL29866044 0.93 CYP3A4 (0.54) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL7015396 0.93 CYP3A4 (0.54) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL30744926 0.91 MAPT (0.57) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL362820 0.91 MAPT (0.57) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL7028593 0.91 MAPT (0.46) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL7016916 0.91 RAB9A (0.58) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL14337759 0.91 TEAD4 (0.55) MAPTALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL7020062 0.91 ALDH1A1 (0.46) MAPTALDH1A1MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103146331-B 4,4'-bis(2,4-diamidophenoxy)biphenyl high-temperature-resistant epoxy adhesive and preparation method thereof DONGHUA UNIVERSITY (CN) 2014-10-15 CN disclosed
CN-103146331-A 4,4'-bis(2,4-diamidophenoxy)biphenyl high-temperature-resistant epoxy adhesive and preparation method thereof UNIV DONGHUA 2013-06-12 CN disclosed