SCHEMBL7015409

SCHEMBL7015409

CCC(C)CSCCc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.47
CYP2D6 P10635 2/20 0.47
CYP2C19 P33261 2/20 0.47
CA2 P00918 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
CES1 P23141 2/20 0.40
TRPA1 O75762 1/20 0.39
MMP12 P39900 1/20 0.39
MMP13 P45452 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
TP53 P04637 1/20 0.38
SIGMAR1 Q99720 4/20 0.38
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9906423 0.82 ACE (0.43) CYP1A2CYP2D6CYP2C19CYP3A4CYP2C9
SCHEMBL598729 0.75 TSHR (0.47) CYP1A2CYP2C19CYP2C9TRPA1SMN1; SMN2
SCHEMBL28774334 0.74 CYP1A2 (0.58) CYP1A2CYP2D6CYP2C19CA2CYP3A4
SCHEMBL10711841 0.74 TSHR (0.46) CYP1A2CYP2C19CYP2C9TRPA1SMN1; SMN2
SCHEMBL9821375 0.74 TSHR (0.46) CYP1A2CYP2C19CYP2C9TRPA1SMN1; SMN2
SCHEMBL577806 0.73 CYP1A2 (0.76) CYP1A2CYP2D6CYP2C19CA2CYP3A4
SCHEMBL8727743 0.73 TRPA1 (0.39) CYP1A2CYP2C19CYP2C9TRPA1SMN1; SMN2
SCHEMBL25141717 0.73 CYP1A2 (0.61) CYP1A2CYP2D6CYP2C19CA2CYP3A4
SCHEMBL10975968 0.72 CYP1A2 (0.55) CYP1A2CYP2D6CYP2C19CA2CYP3A4
SCHEMBL107901 0.72 SIGMAR1 (0.47) SMN1; SMN2SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2233536-B1 Pigment dispersion and ink composition, curable composition and curable ink composition making use of the same FUJIFILM CORP (JP) 2012-05-16 EP disclosed
EP-2233536-A1 Pigment dispersion and ink composition, curable composition and curable ink composition making use of the same Fujifilm Corporation (JP) 2010-09-29 EP disclosed