Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.36 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.36 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL192328 | 0.81 | TDP1 (0.46) | TDP1HTR2AHTR2CHTR2BTSHR | |
| SCHEMBL12280346 | 0.81 | TDP1 (0.37) | TDP1TSHRMAPK1GPR35VCAM1 | |
| SCHEMBL27331521 | 0.81 | TDP1 (0.48) | TDP1HTR2AHTR2CHTR2BTSHR | |
| SCHEMBL4710545 | 0.76 | TDP1 (0.43) | TDP1TSHRMAPK1GPR35ALDH1A1 | |
| SCHEMBL28391943 | 0.73 | TDP1 (0.81) | TDP1HTR2AHTR2CHTR2BTSHR | |
| SCHEMBL22588385 | 0.71 | MERTK (0.53) | TDP1MAPK1ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL1935380 | 0.69 | ALDH1A1 (0.48) | TDP1TSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL28224311 | 0.69 | TDP1 (0.48) | TDP1TSHRMAPK1GPR35VCAM1 | |
| SCHEMBL1460867 | 0.69 | TDP1 (0.61) | TDP1TSHRMAPK1GPR35VCAM1 | |
| SCHEMBL22588351 | 0.68 | L3MBTL1 (0.55) | TDP1MAPK1ALDH1A1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9902858-B2 | Nonlinear optical dye, photorefractive material composition, photorefractive substrate and hologram recording medium | TOYO KOHAN CO., LTD. (JP) | 2018-02-27 | — | — | US | disclosed |
| US-20160230010-A1 | NONLINEAR OPTICAL DYE, PHOTOREFRACTIVE MATERIAL COMPOSITION, PHOTOREFRACTIVE SUBSTRATE AND HOLOGRAM RECORDING MEDIUM | TOYO KOHAN CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
| EP-1368342-A2 | BENZIMIDAZOLE AND PYRIDYLIMIDAZOLE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | NEUROGEN CORPORATION (US) | 2003-12-10 | — | — | EP | disclosed |
| WO-2002050062-A2 | BENZIMIDAZOLE AND PYRIDYLIMIDAZOLE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | NEUROGEN CORPORATION (US) | 2002-06-27 | — | — | WO | disclosed |