Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 16/20 | 0.58 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.56 |
| ▸ | NQO2 | P16083 | 3/20 | 0.54 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7016697 | 0.85 | MTNR1A (0.70) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7015300 | 0.85 | MTNR1A (0.62) | MTNR1AMTNR1BNQO2NOTUM | |
| SCHEMBL7022005 | 0.84 | MTNR1A (0.65) | MTNR1AMTNR1BNQO2NOTUM | |
| SCHEMBL8134979 | 0.82 | MTNR1A (0.64) | MTNR1AMTNR1BNOTUM | |
| SCHEMBL7018584 | 0.80 | MTNR1A (0.71) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7021391 | 0.80 | MTNR1A (0.59) | MTNR1AMTNR1BNOTUM | |
| SCHEMBL8126316 | 0.79 | MTNR1A (0.65) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7023396 | 0.76 | MTNR1A (0.74) | MTNR1AMTNR1BNQO2NOTUM | |
| SCHEMBL7016806 | 0.75 | MTNR1A (0.77) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL5346189 | 0.75 | MTNR1A (0.71) | MTNR1AMTNR1BNQO2NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1057826-B1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-04-16 | — | — | EP | claimed |
| US-6310074-B1 | TREATING MELATONINERGIC DISORDERS | ADIR ET COMPAGNIE (FR) | 2001-10-30 | — | — | US | claimed |
| EP-1057826-A1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-12-06 | — | — | EP | claimed |
| EP-1057826-B1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-04-16 | — | — | EP | disclosed |
| US-6310074-B1 | TREATING MELATONINERGIC DISORDERS | ADIR ET COMPAGNIE (FR) | 2001-10-30 | — | — | US | disclosed |
| EP-1057826-A1 | Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-12-06 | — | — | EP | disclosed |