Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 12/20 | 0.33 |
| ▸ | PIM1 | P11309 | 4/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2976500 | 0.68 | PARP1 (0.46) | PARP1PIM1PDPK1PIM3CHEK1 | |
| SCHEMBL1550252 | 0.68 | KDM4E (0.31) | KDM4EALDH1A1AURKA | |
| SCHEMBL4240700 | 0.67 | CCR8 (0.46) | SMN1; SMN2KDM4ENFKB1MAOAMAOB | |
| SCHEMBL15707647 | 0.63 | GSK3B (0.41) | PARP1PIM1PDPK1PIM3CHEK1 | |
| Quinazolinone SCHEMBL10418 | 0.63 | PARP1 (0.48) | PARP1PIM1PDPK1CHEK1CA12 | |
| SCHEMBL19153215 | 0.62 | MAOA (0.42) | PARP1PIM1PDPK1PIM3CHEK1 | |
| Quinazolinone SCHEMBL7746268 | 0.61 | PARP1 (0.47) | PARP1PIM1PDPK1CHEK1CA12 | |
| Quinazolinone SCHEMBL8201415 | 0.61 | PARP1 (0.47) | PARP1PIM1PDPK1CHEK1CA12 | |
| SCHEMBL7015716 | 0.61 | PNP (0.32) | PARP1PIM1PDPK1PIM3CHEK1 | |
| SCHEMBL19743069 | 0.60 | PARP1 (0.40) | PARP1PIM1SMN1; SMN2CSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | claimed |
| EP-0733633-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |