Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 13/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8686431 | 0.73 | APP (0.35) | HSD11B1APPBACE1BACE2CYP19A1 | |
| SCHEMBL8686102 | 0.73 | APP (0.35) | HSD11B1APPBACE1BACE2CYP19A1 | |
| SCHEMBL19628669 | 0.67 | APP (0.37) | HSD11B1APPBACE1BACE2CYP19A1 | |
| SCHEMBL15974332 | 0.67 | GAA (0.36) | HSD11B1APPBACE1BACE2GAA | |
| SCHEMBL8958230 | 0.67 | GAA (0.36) | HSD11B1APPBACE1BACE2GAA | |
| SCHEMBL15974137 | 0.65 | CCR2 (0.36) | HSD11B1CYP19A1TBXAS1GAAMMP13 | |
| SCHEMBL15974753 | 0.65 | APP (0.38) | HSD11B1APPBACE1BACE2 | |
| SCHEMBL15974011 | 0.64 | GAA (0.36) | GAAMMP13RAB9ASMN1; SMN2 | |
| SCHEMBL5447079 | 0.64 | GAA (0.42) | HSD11B1APPBACE1BACE2CYP19A1 | |
| SCHEMBL15974584 | 0.63 | APP (0.33) | APPBACE1BACE2GAAMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7149693-A | — | — | None | — | — | JP | disclosed |
| EP-1083882-A4 | A HEPATOCYTE TARGETING POLYETHYLENE GLYCO-GRAFTED POLY-L-LYSINE POLYMERIC GENE CARRIER | EXPRESSION GENETICS INC (US) | 2004-08-18 | — | — | EP | disclosed |
| EP-1083882-A1 | A HEPATOCYTE TARGETING POLYETHYLENE GLYCO-GRAFTED POLY-L-LYSINE POLYMERIC GENE CARRIER | Expression Genetics, Inc. (US) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999059546-A1 | A HEPATOCYTE TARGETING POLYETHYLENE GLYCO-GRAFTED POLY-L-LYSINE POLYMERIC GENE CARRIER | EXPRESSION GENETICS, INC. (US) | 1999-11-25 | — | — | WO | disclosed |
| JP-H07149693-A | NOVEL ESTER DERIVED FROM 2,2-DIMETHYL-3-(3,3,3-TRIFLUORO-1-PROPENYL)CYCLOPROPANECARBOXYLIC ACID, ITS PREPARATION AND USE THEREOF AS INSECTICIDE | ROUSSEL UCLAF | 1995-06-13 | — | — | JP | disclosed |
| US-4708869-A | THICKENERS AND FOAM | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1987-11-24 | — | — | US | disclosed |
| EP-0010347-B1 | NOVEL SUBSTITUTED OMEGA-AROYL(PROPIONYL OR BUTYRYL)-L-PROLINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION | AMERICAN CYANAMID COMPANY (US) | 1983-11-09 | — | — | EP | disclosed |
| EP-0012845-A1 | Tetrahydroisoquinoline compounds, process for preparing same and pharmaceutical compositions containing them | Tanabe Seiyaku Co., Ltd. (JP) | 1980-07-09 | — | — | EP | disclosed |
| EP-0006283-A1 | Heterotricyclic compounds, processes for their production and pharmaceutical compositions containing them | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-01-09 | — | — | EP | disclosed |