Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 14/20 | 0.67 |
| ▸ | PDE4B | Q07343 | 14/20 | 0.67 |
| ▸ | PDE4C | Q08493 | 14/20 | 0.67 |
| ▸ | PDE4D | Q08499 | 14/20 | 0.67 |
| ▸ | PDE5A | O76074 | 4/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7020449 | 0.95 | PDE4A (0.76) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL7019337 | 0.90 | PDE4D (0.55) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL7021594 | 0.89 | PDE4D (0.59) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7019218 | 0.85 | PDE4B (0.49) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7014555 | 0.81 | PDE4A (0.75) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7020430 | 0.80 | PDE4A (0.60) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7020796 | 0.80 | PDE4B (0.50) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7019362 | 0.80 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7018517 | 0.79 | PDE4D (0.72) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7016945 | 0.79 | PDE4A (0.52) | PDE4APDE4BPDE4CPDE4DMALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086106-B1 | FUROPYRIDINE DERIVATIVES AND THEIR THERAPEUTICAL USE | DARWIN DISCOVERY LTD (GB) | 2003-08-20 | — | — | EP | claimed |