Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 13/20 | 0.55 |
| ▸ | VCP | P55072 | 1/20 | 0.49 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.48 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.48 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL803614 | 0.87 | CARM1 (0.46) | HRH4CARM1PRMT6PRMT8LDHA | |
| Hydrochloric Acid SCHEMBL784871 | 0.85 | CARM1 (0.46) | HRH4CARM1PRMT6PRMT8LDHA | |
| SCHEMBL7008382 | 0.84 | CARM1 (0.47) | HRH4VCPCARM1PRMT6PRMT8 | |
| SCHEMBL7009989 | 0.82 | CARM1 (0.47) | HRH4CARM1PRMT6PRMT8LDHA | |
| SCHEMBL803613 | 0.79 | HRH4 (0.56) | HRH4CARM1PRMT6PRMT8LDHA | |
| SCHEMBL7107787 | 0.79 | CARM1 (0.44) | HRH4VCPCARM1PRMT6PRMT8 | |
| SCHEMBL16691285 | 0.78 | LDHA (0.47) | HRH4CARM1PRMT6PRMT8LDHA | |
| Hydrochloric Acid SCHEMBL785467 | 0.78 | HRH4 (0.54) | HRH4CARM1PRMT6PRMT8LDHA | |
| SCHEMBL7016109 | 0.77 | VCP (0.57) | VCPCARM1PRMT6PRMT8LDHA | |
| SCHEMBL22886404 | 0.75 | LDHA (0.49) | HRH4LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030187023-A1 | Sulfone derivatives, process for their production and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-10-02 | — | — | US | disclosed |
| EP-1302462-A1 | SULFONE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2003-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187023-A1 | Sulfone derivatives, process for their production and use thereof | SULT1E1, RRS1, SHH | HRH4 87/4885VCP 4310/4885CARM1 241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.